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TAGMe DNA Methylation Kits (qPCR) maka Ọrịa Cancer Endometrial na-ewepụta Oge nke Nchọpụta Ọrịa Cancer Endometrial na Ọgwụ 2.0

Ngwọta maka ọrịa cancer endometrial, na-ewepụ ọrịa cancer na ọkwa nke ọnya ọrịa.Ọrịa cancer endometrial bụ otu n'ime ọrịa kansa atọ kachasị njọ na-arịa ọrịa gynecology.

Ọrịa cancer endometrial bụ otu n'ime ọrịa kansa ọjọọ na-ahụkarị na usoro ọmụmụ ụmụ nwanyị, ọkwa nke abụọ n'ime ajọ usoro ọmụmụ ụmụ nwanyị na China, ma bụrụkwa nke juru ebe niile na ụmụ nwanyị obodo mepere emepe.Dabere na ọnụ ọgụgụ sitere na International Agency for Research on Cancer of the World Health Organisation, enwere ihe dị ka ọrịa 420,000 ọhụrụ nke ọrịa kansa endometrial n'ụwa niile na 2020, na-egbu ihe dị ka 100,000.

N'ime ikpe ndị a, ihe dị ka 82,000 ọhụrụ ọrịa cancer endometrial ka akọọrọ na China, na-egbu ihe dị ka 16,000.A na-eme atụmatụ na n'afọ 2035, a ga-enwe ọrịa cancer endometrial ọhụrụ 93,000 na China.

Ọnụọgụ ọgwụgwọ maka ọrịa kansa endometrial n'oge dị elu nke ukwuu, yana ọnụego ndụ afọ 5 ruru 95%.Agbanyeghị, ọnụọgụ ndụ afọ 5 maka ogbo IV ọrịa kansa endometrial bụ naanị 19%.

Ọrịa cancer endometrial na-adịkarị na ụmụ nwanyị postmenopausal na perimenopausal, yana nkezi afọ mmalite nke ihe dị ka afọ 55.Otú ọ dị, n'afọ ndị na-adịbeghị anya, a na-enwe ọganihu na-arịwanye elu na ọrịa cancer endometrial n'etiti ụmụ nwanyị dị afọ 40 na n'okpuru.

Enweghị usoro nyocha nke ọma maka ọrịa cancer endometrial ugbu a

Maka ụmụ nwanyị nọ n'afọ ịmụ nwa, nyocha mmalite na nlekọta nke ọrịa cancer endometrial n'oge nwere ike ime ka nchekwa nke ọmụmụ dịkwuo elu ma nye ohere maka ịlanarị ogologo oge.

Otú ọ dị, ugbu a, ọ dịghị usoro nyocha nke na-adịghị mma na nke ziri ezi maka ọrịa cancer endometrial na omume ụlọ ọgwụ.A na-eleghara ihe mgbaàmà dịka ọbara ọgbụgba na-adịghị mgbe niile na mpụta nke ikpu na mmalite oge, na-ebute ohere efu maka nchọpụta mmalite.

Nyocha mbụ site na iji foto ultrasound na nyocha nke gynecology oge niile nwere mmetụta dị ala.

Iji hysteroscopy na biopsy pathological na-emerụ ahụ, nke nwere nnukwu mgbakasị ahụ na ọnụ ahịa, ma nwee ike ịkpata ọbara ọgbụgba, ọrịa, na uterine perforation, na-eduga na ọnụ ọgụgụ dị elu nke nchọpụta na-efunahụ, na-ejighị ya dị ka usoro nyocha oge niile.

Nleba anya biopsy nke endometrial nwere ike ịkpata ahụ erughị ala, ọbara ọgbụgba, ọrịa, na perforation nke uterine, na-eduga n'ọkwa dị elu nke nyocha a na-efunahụ ya.

TAGMe DNA Methylation Kits (qPCR) maka ọrịa kansa endometrialNa-ebido Oge nchọpụta Ọrịa Cancer Endometrial na Ọgwụ 2.0

TAGMe DNA Methylation Kits (qPCR) maka ọrịa kansa endometrialnwere ike imeju mmejọ nke ụzọ nyocha nke mbụ maka ọrịa kansa endometrial, na-ebelata ọnụ ọgụgụ nchoputa a na-efunahụ nke ukwuu na inyere ndị ọrịa aka ịchọpụta akara ọrịa kansa n'oge.

Nnwale ihu abụọ bụ "ọkọlọtọ ọla edo" maka nkwado teknụzụ yana ọkọlọtọ ụlọ ọgwụ nke Epiprobe na-agbaso mgbe niile!

Nsonaazụ nke ule kpuru ìsì abụọ gosiri na maka ihe atụ nke scrape cervical, AUC bụ 0.86, kpọmkwem bụ 82.81%, na uche bụ 80.65%;maka ihe atụ ahịhịa uterine cavity, AUC bụ 0.83, nkọwapụta bụ 95.31%, na uche bụ 61.29%.

Maka ngwaahịa a na-enyocha ọrịa kansa n'oge, ebumnuche bụ isi bụ ịchọpụta ndị nwere nsogbu kama ịme nyocha nke ọma.

Maka ngwaahịa nyocha ọrịa kansa n'oge, n'ịtụle na ebumnuche nke onye ọrụ na-eji bụ iwepụ ihe ize ndụ nke ọrịa yana iji zere nchoputa a na-atụghị anya ya dị ka o kwere mee bụ ezi ezi obi nye ndị a nwalere.

The ọjọọ amụma uru nkeTAGMe DNA Methylation Kits (qPCR) maka ọrịa kansa endometrialbụ 99.4%, nke pụtara na n'ime ọnụ ọgụgụ ndị mmadụ na-enweta nsonaazụ na-adịghị mma, 99.4% nke nsonaazụ na-adịghị mma bụ ezi ihe ọjọọ.Ikike igbochi nchoputa a na-atụghị anya ya bụ ihe pụtara ìhè, na ihe ka n'ọnụ ọgụgụ nke ndị ọrụ na-adịghị mma nwere ike ijide n'aka na ọ dịghị ha mkpa ịme nyocha nke mkpasu iwe na ọnụ ọgụgụ nchoputa efu efu.Nke a bụ nchebe kachasị maka ndị ọrụ.

Nyocha onwe onye nke ihe ize ndụ maka ọrịa cancer endometrial.

Site na mmụba nke ụkpụrụ ndụ, ọnụ ọgụgụ nke ọrịa kansa endometrial na China na-abawanye kwa afọ, enwerekwa usoro n'ebe ndị ọrịa na-eto eto nọ.

Yabụ, kedu ụdị mmadụ nwere ike ibute ọrịa kansa endometrial?

N'ikwu okwu n'ozuzu, ndị nwere ike ịmalite ọrịa cancer endometrial nwere àgwà isii ndị a:

  1. Na-ata ahụhụ site na ọrịa metabolic syndrome: ọrịa ji oke ibu, ọkachasị oke ibu nke afọ, yana ọbara shuga dị elu, lipids ọbara na-adịghị mma, ọbara mgbali elu, wdg, nke na-emetụta ahụ ike nke ahụ nke ukwuu;
  2. Mkpali estrogen otu ogologo oge: ikpughe ogologo oge na mkpali estrogen na-enweghị progesterone kwekọrọ iji chebe endometrium;
  3. Oge nsọ nsọ na mbubreyo menopause: nke a pụtara na ọnụ ọgụgụ nke ịhụ nsọ na-abawanye, ya mere endometrium na-ekpughere mkpali estrogen ruo ogologo oge;
  4. Ịmụghị ụmụaka: n'oge ime ime, ọkwa nke progesterone dị n'ime ahụ dị elu, nke nwere ike ichebe endometrium;
  5. Ihe mkpụrụ ndụ ihe nketa: nke kachasị kpochapụ bụ ọrịa Lynch.Ọ bụrụ na e nwere ọrịa ndị na-eto eto nke ọrịa cancer colorectal, ọrịa cancer afọ, ma ọ bụ ndị ikwu nwanyị nwere ọrịa cancer ovarian, ọrịa cancer endometrial, wdg n'etiti ndị ikwu ya, ekwesịrị iburu n'uche na ndụmọdụ mkpụrụ ndụ ihe nketa na nyocha;
  6. Àgwà ndụ na-adịghị mma: dị ka ise siga, enweghị mmega ahụ, na mmasị maka nri ndị nwere calorie na abụba dị elu dị ka ibe poteto, fries french, tii mmiri ara ehi, nri eghe, achịcha chocolate, wdg, ya mere ọ dị mkpa iji mgbatị ahụ. ọzọ mgbe riri ha.

Ị nwere ike iji onwe gị tụnyere njirimara 6 dị n'elu nke nwere ike ịmalite ọrịa cancer endometrial, ma gbalịa imezi ha dịka o kwere mee iji gbochie ya site na isi iyi.

 


Oge nzipu: Mee-09-2023